Do not use if you are under 12 years old or if you have had a heart attack, stroke, or have circulation problems unless directed by your doctor. Consult your doctor before use if you are pregnant, breastfeeding, or have conditions such as high blood pressure, stomach ulcer, kidney or liver disease, overactive thyroid, or adrenal gland cancer. Possible side effects include gastrointestinal discomfort due to ingredients like mannitol and xylitol, which may have a laxative effect.